ARE THERE PROTEINS IN THE TOOTH THAT STIMULATE BONE GROWTH?

These are all the proteins in common between bone and tooth, in this article you will find the details of the search.


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WHY CAN YOU USE THE TOOTH AS GRAFTING MATERIAL?

Because the tooth is mineralized bone.


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WHY CAN THE DECIDUOUS TOOTH BE USED AS GRAFTING MATERIAL?

The deciduous tooth can be demineralized and used as a grafting material.


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CAN A DECIDUOUS TOOTH BE USED AS GRAFTING MATERIAL?

In this case report the authors show a clinical case where deciduous teeth extracted 15-20 years earlier and stored in a container were used. The clinical case is presented by histological analysis and clinical follow-up.


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DOES THE DECIDOUS TOOTH, TREATED WITH TT TRANSFORMER, CONTAIN MORPHOGENETIC PROTEINS?

Yes, both BMP and type 1 collagen were measured in this article.


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DOES THE TOOTH TREATMENT HAVE ANY EFFECT OR CAN I USE THE GRANULATE WITHOUT TREATMENT?

This article shows that the tooth must be treated in order to be successful. Without treatment no bone is formed (fig.1). With treatment bone is formed (fig.2) as shown in the pictures.


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CAN YOU USE THE TT TRANSFORMER
FOR SINUS LIFT ?

Yes! In this article ( 1 ), which precedes the multicenter breast augmentation study, 4 cases of sinus lift were analyzed.
Yes. In this multicenter study ( 2 ) 23 patients were analyzed and 40 implants were placed. The implant success rate at 19 months is 97.5%.


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CAN DEVITALIZED TEETH BE USED FOR SINUS LIFT?

Yeah. In this multicenter study, 83% of the teeth used were devitalized.


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IS BONE FORMED BY USING THE TOOTH AS GRAFT MATERIAL FOR SINUS LIFT?

Yes. Here are the histomorphometric data (analysis of the contents of a bone biopsy sample).


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CAN TEETH BE TREATED WITH TT TRANSFORMER AND USED AS GRAFTING MATERIAL?

In the article Prof. Paolo Trisi tells about his new experiences with the TT Transformer.


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IS IT POSSIBLE TO USE A TOOTH AS REGENERATION MATERIAL?

In this article the authors study a protocol for the use of the tooth as a regeneration material and analyze various aspects in vitro.


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IS THE NORMAL BACTERIAL LOAD ON THE EXTRACTED TOOTH SEVERELY REDUCED INTO THE GRANULES AFTER THE TREATMENT?

Yes, as shown in this article and in the picture the granules obtained after the treatment are free of bacteria.


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HOW HAS THE BIOCOMPATIBILITY OF THE TOOTH BEEN DEMONSTRATED AFTER TT TRANSFORMER TREATMENT?

Numerous in vitro tests have been carried out showing how osteoblasts adapt to the surface of pre and post treatment granules.


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AFTER TREATMENT WITH TT TRANSFORMER ARE BMP AND COLLAGEN PRESENT?

Acids can destroy proteins. The tests performed by the authors of the following article have evaluated and demonstrated that the treatment done by the TT Transformer allows to have the maximum available protein in the tooth.


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IF THE TOOTH IS TREATED IN DIFFERENT WAYS THAN TT TRANSFORMER WHAT HAPPENS?

The results obtained using the TT Transformer can only be replicated using our device. Any other tooth treatment does not guarantee the same results. Prof. Kim in this article demonstrates that the tooth contains proteins and any protein can be affected by different types of liquids. The properties of treated dentin depend on the different treatment protocols.


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IF WE USE DIFFERENT TOOTH TREATMENT PROTOCOLS, WHAT HAPPENS?

In these articles, the authors explain that the differently treated tooth may also not produce bone during the regeneration phases. Our protocol has shown (through multicenter studies carried out) that it is able to produce bone in every situation of use.


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ARE THERE ANY DOCUMENTED CLINICAL CASES IN THE LITERATURE USING TT TRANSFORMER?

In this article, anticipation of multicentre studies, the use of the TT Transformer in 15 consecutive cases is analysed.


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ARE THERE DOCUMENTED CLINICAL CASES WITH HISTOLOGIES OF DENTAL TREATMENT WITH TT TRANSFORMER?

In this article 11 consecutive cases of socket preservation are analyzed, also evaluating histological results.


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IS IT POSSIBLE TO ASSOCIATE TT TRANSFORMER WITH OTHER SURGICAL TECHNIQUES?

Dental material can be used in any technique in association with any material. In these articles, by Spanish authors, the use of the TT Transformer is associated with the socket shield technique.


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IS IT POSSIBLE TO ASSOCIATE TT TRANSFORMER WITH OTHER SURGICAL TECHNIQUES?

Dental material can be used in any technique in association with any material. In this article, by Spanish authors, the use of the TT Transformer is associated with the use of PRP.


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IS THERE ANY DOCUMENTATION ON THE USE OF DECIDUOUS TEETH WITH THE TT TRANSFORMER?

Yes, this article 'case report', in publication, analyses the results of the only case in the world made with a single deciduous tooth. The results are not only clinical but also histological and histomorphometric.


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ARE THERE HISTOLOGIES ABOUT USING DECIDUOUS TEETH WITH TT TRANSFORMER?

Yes, this article 'case report' analyzes the results of the only case in the world made. The results are not only clinical, but also histological and histomorphometric.


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HOW DO I KNOW HOW MUCH MATERIAL I WILL HAVE PRODUCED AFTER USING TT TRANSFORMER?

In this article 205 teeth have been analyzed to answer the question. The TT TRANSFORMER is able to produce 100% of the weight of the tooth and therefore a 1:1 ratio between tooth weight and weight of the final product.


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IS IT POSSIBLE TO COMPARE THE PERFORMANCE OF THE TT TRANSFORMER WITH OTHER BIOMATERIALS?

In this article the results obtained by mixing equal parts of the material produced by the TT Transformer with xenographic material were analysed, comparing them to the use of the TT Transformer product alone. The results are shown in the table and in the in-depth analysis.


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ARE THE COMPARISON DATA SUPPORTED BY HISTOLOGIES?

In this article the data collected are supported only by histological evidence.


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ARE THERE DIFFERENCES BETWEEN GRANULATE OBTAINED FROM DEVITALIZED AND HEALTHY TEETH?

To date, as this multicentre study being published shows, there are no differences.


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IS IT POSSIBLE TO ESTABLISH A HIGHER OR LOWER LEVEL OF EFFECTIVENESS BETWEEN THE DIFFERENT BONE GRAFTS DERIVED FROM THE TOOTH?

The article describes that the lack of adequate uniformity and standardization in the processing of the material makes it impossible to compare the various grafting materials derived from the tooth. Considering that each treatment leads to a different result, it can be stated that the results obtained using the TT transformer, based on extensive documentation of in vitro, histological and clinical studies, can only be obtained using the TT Transforme medical device. This systematic review has clearly demonstrated the diversity of treatment methods used to produce tooth derived graft material. There is no standardisation of source (autologous, xenographic, allographic), treatment (materials and methods for demineralisation and sterilisation), composition (dentine, enamel, cement) and size (particle size). The absence of adequate uniformity and standardization in the pro cessation of the material makes it impossible to compare the various materials and also does not provide definitive results on the clinical efficacy of dental grafting material. Clinical Efficacy of Tooth-Bone Graft: A Systematic Review and Risk of Bias Analysis of Randomized Control Trials and Observational Studies Amit S. Gharpure, BDS* and Neel B. Bhatavadekar, BDS, MS, MPH IMPLANT DENTISTRY / VOLUME 27, NUMBER 1 2018.


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